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The Pioneer in Aptamer Technology
Genicore is deeply dedicated to Genimer™ aptamer development, striving to overcome traditional antibody limitations and provide the global biomedical community with more precise, stable, and highly efficient research and clinical solutions

Aptamer applications

Our Journey

Genicore was established at the core of Taiwan's biomedical innovation hub, uniting a multidisciplinary team of experts in biomedicine, AI computation, and molecular simulation. Recognizing that traditional antibodies—despite their vital role—face persistent limitations in cost, stability, and development speed, we saw a clear bottleneck restricting the growth of precision medicine.

Driven to bypass this obstacle, we engineered the Genimer™ platform, seamlessly integrating aptamer technology with AI simulation. This innovation does more than upgrade technology; it redefines the very logic of biological detection.

Beginning as a nascent technology at the Chang Gung University Innovation Incubation Center, Genicore has evolved into a trusted, critical collaborator for prominent pharma companies and research institutes. Anchored by rigorous scientific data, we are dedicated to closing the gap between lab research and clinical reality—ensuring advanced biomedical diagnostics are highly precise and universally accessible.

Core Technologies

Aptamer RD

Aptamer

Aptamers are single-stranded oligonucleotides known as "chemical antibodies." With their small size, high flexibility, and exceptional specificity, they achieve precision target recognition from ions to whole cells—outperforming traditional antibodies in versatility. Leveraging this, Genicore engineers our world-leading, next-generation Genimer™ aptamers.

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Advantages of Genimer™ over Antibodies

Genimer™ eliminates thermal denaturation and batch instability. At just 1/10 the molecular weight of an antibody, it offers superior tissue penetration and crosses the blood-brain barrier (BBB). With thermal stability above 90°C, room-temperature storage, and 100% chemical synthesis, Genimer™ ensures 0% batch variation at a fraction of the cost—slashing development to under two weeks.

Aptamer

Genimer™ Aptamer Screening Platform

  • Structural Conformation: Short sequences boost loop formation, specificity, and stability.

  • 7-14 Day Timelines: Slashes screening to 5–10 rounds, delivering results over 2X faster.

  • Next-Gen NGS Analysis: Maps high-frequency candidate sequences to eliminate blind spots.

  • AI Pre-Screening: Utilizes molecular docking simulations to cut laboratory overhead.

  • Affinity Maturation: Optimizes sequences via proprietary software for ultra-stable ligands.

Corporate Vision

Beyond Antibodies: Pioneering a New Global Standard in Biodetection

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Genicore is translating Genimer™ technology into a global standard, scaling aptamers from high-end labs into industrial-grade, large-scale deployment. By overcoming traditional antibody limits—such as animal dependency, high costs, and batch inconsistency—our standardized framework delivers superior performance at a fraction of the cost, making precision biological tools the bedrock infrastructure for global healthcare.

Accelerating Biopharma Development via AI Digital Twins

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In biomedical R&D, time is the ultimate cost. Genicore utilizes AI molecular simulation and automated SELEX to slash ligand development timelines from months to mere weeks. By adopting a "digital twin" approach—screening in-silico before lab validation—we exponentially boost success rates and fast-track tools for emerging diseases and rare drug pipelines.

Precision Capture for Personalized Management

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Driven by absolute specificity and sensitivity, Genicore leverages the small size and superior permeability of Genimer™ to detect micro-signals beyond the reach of traditional antibodies. By eliminating background interference, we deliver artifact-free biological data—establishing a robust foundation for early cancer detection, liquid biopsy, and tailor-made personalized healthcare.

Taiwan-Rooted, Globally Driven: The Aptamer Ecosystem

Anchored in Taiwan with a global footprint, Genicore is pioneering a green biotech revolution. By utilizing chemical synthesis for aptamer production, we eliminate laboratory animal testing to meet modern ESG benchmarks. Over the next five years, we aim to forge a complete global value chain across diagnostics, therapeutics, and research—shaping a more precise, humane, and sustainable future for healthcare.

Core Team

Andy Hua

Founder & CEO

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Koyo Chu

R&D Director

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