His-Tag Protein Purification Kits
This nickel-free kit offers high-affinity, metal-free His-tagged protein capture. With ultra-low non-specific binding and zero batch variation, it preserves native activity for high-purity isolation.
His-Tag Protein Genimer™ Purification Kit
Driven by our proprietary Genimer™ aptamer technology, Genicore’s His-Tag Protein Purification Kit introduces a metal-ion-free, high-purity alternative to traditional Ni-NTA methods.
While His-tag is the industry standard for protein isolation, conventional nickel beads often suffer from metal leaching, high non-specific binding, and sample contamination.
Designed for high-affinity capture of His-tagged proteins, this kit replaces metal chelation with fully chemically synthesized aptamers.
The resulting workflow is exceptionally mild and entirely free of metal contaminants, fully preserving the protein's native conformation and biological activity—making it the ideal choice for high-purity protein production and biophysical analysis.
Product Highlights
- 🚫 Metal-Free Isolation: Eliminates traditional nickel chelation, completely preventing metal ion leaching to safeguard downstream enzyme assays and cell cultures.
- 🔬 Ultra-Low Non-Specific Binding: High target specificity drastically reduces background protein noise, delivering ultra-high purity in a single purification step.
- 🧬 Zero Batch-to-Batch Variation: Fully chemically synthesized to guarantee absolute consistency in affinity and binding capacity, overcoming the stability issues of biological antibodies.
- 🌡️ Exceptional Chemical Stability: Exceptional resistance to temperature and pH variations allows compatibility with diverse buffer setups and highly efficient room-temperature operation.
- ⚡ Rapid & Gentle Elution: Combines competitive elution with a streamlined workflow to capture and recover proteins quickly, minimizing the risk of in vitro protein denaturation.