Custom Aptamer Services
Next-Gen Genimer™ Screening
By integrating AI simulation with NGS, Genicore overcomes traditional SELEX bottlenecks. We deliver precise, custom aptamer screening featuring three core advantages: fast timelines, high throughput, and superior affinity.
1. About Genicore
"Breaking biomedical boundaries, anchoring the future of healthcare."Genicore is dedicated to cutting-edge biotech R&D. Through relentless scientific innovation, we provide high-performance technical support for global biodetection, precision medicine, and drug development—empowering our clients to conquer evolving healthcare challenges.
2. Genimer™ Advanced Screening Platform
Aptamers, widely known as "chemical antibodies," are celebrated for their exceptional stability and low immunogenicity. By fusing multi-dimensional technological modules, Genicore has engineered the proprietary Genimer™ Aptamer Screening Platform.
5 Core Integrated Technologies
AI Predictive Modeling: Leverages big data to predict aptamer libraries and precisely pinpoint candidate sequences.
Optimized SELEX: Enhances conventional ligand evolution protocols to drastically boost screening efficiency.
Precision NGS Monitoring: Tracks the entire molecular evolution process via Next-Generation Sequencing to ensure absolute data depth.
Molecular Dynamics: Simulates aptamer-target binding conformations in-silico to optimize affinity.
High-Efficiency Workflow: Standardized, automated operations that sharply reduce the timeline from lab to market.
3. Platform Advantages: Why Choose Genimer™?
Compared to traditional SELEX services, our platform maximizes your R&D value:
Feature | Genimer™ Platform | Traditional SELEX |
Development Timeline | Ultra-fast delivery in weeks | Prohibitive, month-long process |
Throughput | High-throughput parallel screening | Low-throughput; highly limited targets |
Precision | AI + Molecular docking for maximum specificity | Experience-dependent with higher uncertainty |
Affinity | Superior pM-level affinity | Highly variable affinity results |
4. Custom Development Process
We offer a comprehensive, "one-stop" custom workflow tailored precisely to your targets (proteins, small molecules, viruses, or whole cells):
1. Requirement Assessment – Feasibility analysis customized to your specific target.
2. Sequence Screening – Multi-round in-vitro evolutionary selection via the Genimer™ platform.
3. Performance Validation – Rigorous testing of aptamer affinity (Kd value) and specificity.
4. Delivery & Reporting – Comprehensive package including sequence data, binding analytics, and application insights.