Aptamer-conjugated bacteria have shown enhanced anti-tumor efficacy and targeted tumor localization, potentially improving cancer biotherapy.

Current diagnostic methods for dengue fever, such as serological tests, have limitations regarding cross-reactivity with other viruses. A novel dengue virus diagnostic method, combining aptamer technology with Loop-mediated Isothermal Amplification (LAMP), has shown extremely high specificity with no cross-reactivity observed when tested against other viral samples, including Zika virus.

A wearable cortisol aptamer sensor can detect cortisol levels as low as approximately 1 nM from real sweat within minutes, making it a flexible and rapid method for monitoring stress hormones.